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Penn Bioinformatics Profiling Identifies a New Mammalian Clock Gene

22 Apr 2014 – Over the last few decades researchers have characterized a set of clock genes that drive daily rhythms of physiology and behavior in all types of species, from flies to humans. Over 15 mammalian clock proteins have been identified, but researchers surmise there are more. A team from the Perelman... Read more

Penn Medicine Researchers Uncover Hints of a Novel Mechanism Behind General Anesthetic Action

22 Apr 2014 – New research led by the Perelman School of Medicine at the University of Pennsylvania investigated the common anesthetic sevoflurane and found that it binds at multiple key cell membrane protein locations that may contribute to the induction of the anesthetic response. Read more

Sleeping Away Infection: Penn Researchers Find Link between Sleep and Immune Function in Fruitflies

22 Apr 2014 – When we get sick it feels natural to try to hasten our recovery by getting some extra shuteye. Researchers from the Perelman School of Medicine at the University of Pennsylvania found that this response has a definite purpose, in fruitflies: enhancing immune system response and recovery to... Read more

Reference Pricing for Proton Therapy Will Help Establish Clinical Benefits, Say Penn Radiation Oncologists

21 Apr 2014 – Penn Medicine researchers have proposed "reference pricing"a relatively new model that establishes a standard price for different therapies with similar outcomes. It would expand the patient base because of increased, cheaper coverage and thus research to establish whether its novel advantages... Read more

Safer Alternatives to Nonsteroidal Antinflamatory Pain Killers

21 Apr 2014 – Building on previous work that showed that deleting an enzyme in the COX-2 pathway in a mouse model of heart disease slowed the development of atherosclerosis, a Penn Medicine team has now extended this observation by clarifying that the consequence of deleting the enzyme mPEGS-1 differs, depending... Read more

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